About c4c

c4c (conect4children) is a large collaborative European network that aims to facilitate the development of new drugs and other therapies for the entire paediatric population. 

c4c is a pioneering opportunity to build capacity for the implementation of multinational paediatric clinical trials whilst ensuring the needs of babies, children, young people and their families are met. 

This large collaborative European network endeavours to provide a sustainable, integrated platform for the efficient and swift delivery of high-quality clinical trials in children and young people across all conditions and phases of the drug development process.

c4c has been made possible thanks to a novel collaboration between the academic and the private sectors, which includes 35 academic and 10 industry partners from 20 European countries, and more than 50 third parties and around 500 affiliated partners. 

This project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement No 777389. The Joint Undertaking receives support from the European Union’s Horizon 2020 research and innovation programme and EFPIA.

Vision and Mission

c4c Network Vision

Better medicines for babies, children and young people through a pan-European clinical trial network. 

c4c Network Mission

c4c will use a coordinated approach to deliver high quality “regulatory grade” clinical trials in:

  • Multiple countries
  • Multiple sites
  • All paediatric age groups

by supporting:

  • Trial implementation using resources shared between studies
  • Trial design through a combination of information about natural history, feasibility, appropriate innovation, and expert opinion
  • Education and awareness within and beyond the network.

Objectives 

c4c promotes innovation in the design of paediatric clinical trials and quantitative methods in order to foster the development of new medicines in rare paediatric diseases and high medical needs areas.

c4c aims to generate a sustainable infrastructure that optimizes the delivery of clinical trials in children through:

a) a single point of contact for all sponsors, sites and investigators;

b) efficient implementation of trials, adopting consistent approaches, aligned quality standards and coordination of sites at national and international level;

c) collaboration with specialist and national networks;

d) high quality input into study design and preparation, through rigorous strategic and operational feasibility assessment;

e) the promotion of innovative trial design and quantitative scientific methods;

f) an education and training platform to shape the future leaders of paediatric drug development;

g) the development of sustainable support for all these activities.

 

Find out more

 

This project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement No 777389.
The Joint Undertaking receives support from the European Union’s Horizon 2020 research and innovation programme and EFPIA.

 

KD-CAAP
Coordinating Centre

MRC Clinical Trials Unit at UCL
90 High Holborn
2nd Floor 
London
WC1V 6LJ

Email: mrcctu.kdcaap@ucl.ac.uk